creatinine clearance


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Related to creatinine clearance: Creatinine clearance test, Serum creatinine

cre·at·i·nine clear·ance

measurement of the clearance of endogenous creatinine, used for evaluating the glomerular filtration rate.

creatinine clearance

Nephrology The ratio of the rate of creatinine excretion in urine to its concentration in serum, a value that reflects the body's ability to excrete creatinine; it is used to diagnose and monitor renal function

cre·at·i·nine clear·ance

(krē-at'i-nin klēr'ăns)
A mathematical calculation of the total amount of creatinine excreted in the urine over a period of time, usually 24 hours to test renal function. The calculation is: creatinine clearance (mL/minute) = urine creatinine concentration (mL/dL) × volume of urine (mL/24 hour) ÷ plasma creatinine concentration (mg/dL) × 1440 minute/24 hour.

clearance

the act of clearing; it is a primary pharmacokinetic parameter which describes irreversible removal of a drug from the body by all processes and is made up of renal clearance and metabolic clearance.

blood-urea clearance
the volume of the blood cleared of urea per minute by renal elimination.
Bromsulphalein clearance
see sulfobromophthalein clearance test.
creatinine clearance
inulin clearance
see inulin clearance.
clearance time
the time required for a drug to be eliminated after administration. Eliminated means to the point where it can no longer be detected. Of most importance in avoiding drug residues in food animals and charges of doping in sports animals.
urea clearance
blood-urea clearance.
References in periodicals archive ?
Drugs that can interfere with creatinine clearance measurements include cimetidine, trimethoprim, and nephrotoxic drugs, such as cephalosporins (cefoxitin).
Correlation of serum creatinine, and creatinine clearance in the study groups shows that there was negative correlation of [T.
The creatinine clearance has been widely used as only alternative to inulin clearance in routine practice.
Preservation of renal function following partial or radical nephrectomy using 24-hour creatinine clearance.
We used the Cockcroft-Gault formula (5) to calculate creatinine clearance rate in mL/min from serum creatinine [in jwmol/L: creatinine clearance = {(140 - age) x weight (kg) x F}/(serum creatinine X 0.
Robert S, Zarowitz BJ, Peterson EL, Dumler E Predictability of creatinine clearance estimates in critically ill patients.
The original iteration of the eGFR calculation to determine estimated creatinine clearance used age, weight and gender to massage the serum creatinine value.
Elevation of C-reactive protein, interleukin-6, creatinine clearance, and ST-segment depression was also related to a higher mortality.
Increased cadmium was also associated with decreased creatinine clearance, reflecting a reduced glomerular filtration rate.
CHE administration decreased arterial blood pressure dose-dependently followed by a significant rise in creatinine clearance and a fall in fractional post-proximal sodium excretion was compared to the control group.
0 and a total creatinine clearance of at least 60 liters per week.
Perhaps the most useful features for family physicians are unit conversions and what is labeled physiologic profiling," which includes body surface area calculations, fluid balance equations, anion gaps, estimated creatinine clearance, and Glasgow Coma Scale, for example.

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