creatinine


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Related to creatinine: bun, creatine

creatinine

 [kre-at´ĭ-nin]
a nitrogenous compound formed as the end product of creatine metabolism. It is formed in the muscle in relatively small amounts, passes into the blood and is excreted in the urine. A laboratory test for the creatinine level in the blood may be used as a measurement of kidney function (see creatinine clearance).
creatinine clearance test a test of renal function based on the rate of creatinine clearance.

cre·at·i·nine (Cr),

(krē-at'i-nēn, -nin), Do not confuse this word with creatine.
A component of urine and the final product of creatine catabolism; formed by the nonenzymatic dephosphorylative cyclization of phosphocreatine to form the internal anhydride of creatine.

creatinine

/cre·at·i·nine/ (kre-at´ĭ-nin) an anhydride of creatine, the end product of phosphocreatine metabolism; measurements of its rate of urinary excretion are used as diagnostic indicators of kidney function and muscle mass.

creatinine

(krē-ăt′n-ēn′, -ĭn)
n.
A creatine anhydride, C4H7N3O, formed by the metabolism of creatine, that is found in muscle tissue and blood and normally excreted in the urine as a metabolic waste.

creatinine

[krē·at′inēn, -nin]
a substance formed from the metabolism of creatine, commonly found in blood, urine, and muscle tissue. It is measured in blood and urine tests as an indicator of kidney function. Normal adult blood levels of creatinine are 0.5 to 1.1 mg/dL for females and 0.6 to 1.2 mg/dL for males; the numbers decrease in elderly patients because of a smaller muscle mass. See also creatine.

creatinine

Nephrology The end product of creatine metabolism, which is excreted into the urine; creatinine can be used to diagnose and monitor renal failure; creatinine may be measured in amniotic fluid to determine gestational age–fetal maturity index; normal ranges vary according to the lab. See Creatinine clearance.

cre·at·i·nine

(Cr) (krē-at'i-nin)
A component of urine and the final product of creatine catabolism; formed by the nonenzymatic dephosphorylative cyclization of phosphocreatine to form the internal anhydride of creatine.

creatinine

A breakdown product of the important nitrogenous metabolic substance CREATINE. Creatinine is a normal metabolic waste substance and is found in muscle and blood and excreted in the urine.

creatinine

the nitrogenous waste material of muscle creatine.

Creatinine

The metabolized by-product of creatine, an organic acid that assists the body in producing muscle contractions. Creatinine is found in the bloodstream and in muscle tissue. It is removed from the blood by the kidneys and excreted in the urine.

creatinine

breakdown product of creatine in muscle, released into the blood and filtered out by the kidneys; measurements in blood and urine are used as an indicator of renal function. Blood level of creatinine is related to muscle mass.

cre·at·i·nine

(Cr) (krē-at'i-nin)
A component of urine and the final product of creatine catabolism; formed by the nonenzymatic dephosphorylative cyclization of phosphocreatine to form the internal anhydride of creatine.

creatinine (krēat´ənēn´),

n a substance formed from the metabolism of creatine, commonly found in blood, urine, and muscle tissue.

creatinine

a nitrogenous compound formed as the irreversible end product of creatine metabolism. It is formed in the muscle in relatively small amounts, passes into the blood and is excreted in the urine.
A laboratory test for the creatinine level in the blood may be used as a measurement of kidney function. Since creatinine is normally produced in fairly constant amounts as a result of the breakdown of phosphocreatine and is excreted in the urine, an elevation in the creatinine level in the blood indicates a disturbance in kidney function.

creatinine:blood urea nitrogen ratio
determination of blood creatinine and blood urea nitrogen (BUN) and the relationship between them is an additional assessment of renal function. It may be useful in the differential diagnosis of azotemia and in monitoring renal disease when protein-restricted diets are being given.
creatinine clearance test
a measure of renal function based on the rate at which ingested creatinine is filtered through the renal glomeruli.
creatinine:cortisol ratio
see cortisol:creatinine ratio.
creatinine-protein ratio
protein-creatinine ratio.
urine creatinine/serum creatinine ratio
used to distinguish between prerenal and renal azotemia.
References in periodicals archive ?
Serum creatinine was measured at our institute's automatic laboratory using the Jaffe reaction principle.
A urine creatinine test is by itself not a reliable indicator of kidney function.
As noted above, the use of equations that include demographics has revolutionized our ability to use serum creatinine to estimate GFR.
This is not to say that acute creatinine increases are free of associated risk.
7,11) These technically demanding experiments were designed to elucidate the mechanisms of creatinine excretion in chickens compared with other species.
For each lot of material, final concentrations of creatinine in selected samples are measured by liquid-chromatography isotope-dilution mass spectrometry at NIST.
The relationship between serum creatinine and FBS, adjusting with sex, level of BMI and drug treatment effects has been studied.
The measuring units of both the urine and plasma creatinine concentrations have to be adjusted to the same units (either mmol/l or [mu]mol/l) so that the CrCl is reported in plasma volume cleared of creatinine (ml) per unit time (min).
Moreover, one in six subjects who were found to have CKD by the triple-marker method were not identified at all by creatinine level alone, suggesting that people could have occult CKD that would not be diagnosed according to standard methods.
The update is intended to prevent drug overdosing of children with low body weight, low body surface area, and very low serum creatinine.
In routine practice, serum creatinine concentrations are used as a key biochemical index of glomerular filtration, the assessment of which is a central factor in appropriate drug dosing.

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