creatine phosphate


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phos·pho·cre·a·tine

(fos'fō-krē'ă-tēn),
A phosphagen; a compound of creatine (through its NH2 group) with phosphoric acid; a source of energy in the contraction of vertebrate muscle, its breakdown furnishing phosphate for the resynthesis of ATP from ADP by creatine kinase. Compare: phosphoarginine.

creatine phosphate

creatine phosphate (CP)

Etymology: Gk, kreas, flesh; Du, potasschen
an enzyme that increases in blood levels when muscle damage has occurred, as in pseudohypertrophic muscular dystrophy.

phos·pho·cre·a·tine

(PCr) (fos'fō-krē'ă-tēn)
A phosphagen; a compound of creatine with phosphoric acid; a source of energy in the contraction of vertebrate muscle, its breakdown furnishing phosphate for the resynthesis of adenosine triphosphate from adenosine diphosphate by creatine kinase.
Synonym(s): creatine phosphate, Nω-phosphonocreatine.

creatine phosphate

see PHOSPHAGEN.

creatine

a nonprotein nitrogen substance synthesized in the body from three amino acids: arginine, glycine (aminoacetic acid) and methionine. Creatine readily combines with phosphate to form phosphocreatine, or creatine phosphate, which is present in muscle, where it serves as the storage form of high-energy phosphate necessary for intense muscle contraction.

creatine kinase (CK)
an organ-specific enzyme catalyzing the transfer of a phosphate group from phosphocreatine to ATP. It has three isoenzymes: CK1, found primarily in the brain; CK2, found in the myocardium; and CK3, found in both skeletal muscle and the myocardium. In humans, the presence of CK2 in the blood is useful in diagnosing a recent myocardial infarction, but in animals CK3 is most commonly increased related to muscle damage. Called also creatine phosphokinase, Lohmann's enzyme.
creatine phosphate
see creatine (above).
creatine phosphokinase
called also CPK; see creatine kinase (above).
References in periodicals archive ?
Simultaneous determination of myocardial nucleotides, nucleosides, purine bases and creatine phosphate by ion-pair high-performance liquid chromatography.
CK plays a major role in fast muscle contraction by supplying creatine phosphate, which is used for ATP production, especially under anaerobic conditions.
m] values of r-hCK-MB for creatine phosphate (CP) and ADP were determined under conditions described in the Japanese method with CP and ADP at concentrations of 0.
During muscle contraction, creatine and creatine phosphate are spontaneously converted to creatinine.

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