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A substance promoted in the late 1940s as an effective therapy for cancer, which in samples obtained by the NCI and the FDA consisted of creatine monohydrate in mineral oil. Of the 4307 Krebiozen-treated cases investigated by the FDA, less than one-half of the medical records were complete enough to allow evaluation; only three of these 1526 cases had what would be considered objective responses, and the three cases may have represented spontaneous regression of cancer. The healthcare professionals of the Krebiozen Research Foundation were indicted on 49 counts of fraud and conspiracy, but were acquitted.
cre·a·tine mon·o·hy·drate(krē'ă-tin mon'ō-hī'drāt)
A physiologic amino acid that is taken as a supplement by athletes to improve performance; gastrointestinal complaints common; suggested cause of impaired renal function.