creatine (redirected from creatine kinase (CK))

creatine /cre·a·tine/ (kre´ah-tin) an amino acid occurring in vertebrate tissues, particularly in muscle; phosphorylated creatine is an important storage form of high-energy phosphate.

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creatine phosphate  phosphocreatine.

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cre·a·tine (kr-tn, -tn) or cre·a·tin (-tn)

n.

A nitrogenous organic acid that is found in the muscle tissue of vertebrates mainly in the form of phosphocreatine and supplies energy for muscle contraction.

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creatine

[krē′ətēn, -tin]

Etymology: Gk, kreas, flesh

an important nitrogenous compound produced by metabolic processes in the body. Combined with phosphorus, it forms a high-energy phosphate. In normal metabolic reactions the phosphorus is transferred to a molecule of adenosine diphosphate to produce a molecule of very high-energy adenosine triphosphate. See also creatinine.

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creatine (krēˑ··tīn),

n an amino acid that is created in the body in the kidneys, liver, and pancreas. Used as a supplement by athletes to aid in performance. Not for use by pregnant or nursing women, children, or patients with kidney or heart disease.

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creatine

a nonprotein nitrogen substance synthesized in the body from three amino acids: arginine, glycine (aminoacetic acid) and methionine. Creatine readily combines with phosphate to form phosphocreatine, or creatine phosphate, which is present in muscle, where it serves as the storage form of high-energy phosphate necessary for intense muscle contraction.

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creatine kinase (CK)

an organ-specific enzyme catalyzing the transfer of a phosphate group from phosphocreatine to ATP. It has three isoenzymes: CK₁, found primarily in the brain; CK₂, found in the myocardium; and CK₃, found in both skeletal muscle and the myocardium. In humans, the presence of CK₂ in the blood is useful in diagnosing a recent myocardial infarction, but in animals CK₃ is most commonly increased related to muscle damage. Called also creatine phosphokinase, Lohmann's enzyme.

creatine phosphate

see creatine (above).

creatine phosphokinase

called also CPK; see creatine kinase (above).

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Patient discussion about creatine kinase (CK).

Q. Q. I want to know about urine protein creatine ratio in diagnosing nephrotic syndrome. Please explain interms of unit such as mg/mg or mmol/mg. Normal range, nephrotic range with good referrence.

A. Nephrotic syndrome is defines as a damage to the kidneys, in which there is a leak of large amounts of protein (over 3.5 grams of protein / 24 hours urine output) from the blood to the urine. Protein loss causes low protein count in the blood (hypoalbuminemia) and edemas (excess fluid in the interstitial cavity which is between the cells, causes leg swelling most often, and also in the adbomen and around the eyes).