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cowpox

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cowpox /cow·pox/ (kou´poks) a mild eruptive disease of milk cows, confined to the udder and teats, due to cowpox virus, and transmissible to humans.
cow·pox (koupks)
n.
A mild, contagious skin disease of cattle, usually affecting the udder, that is caused by a virus and characterized by the eruption of a pustular rash. When the virus is transmitted to humans, as by vaccination, it can confer immunity to smallpox. Also called vaccinia.

cowpox
[kou′poks]
Etymology: AS, cu + ME, pokkes
a mild infectious disease characterized by a pustular rash, caused by the vaccinia virus. Animals that carry the vaccinia virus are cows, cats, and rodents. Human cases are usually rare. Transmission to humans can occur during the milking of a cow with active lesions on the udder and teats, but the disease is usually transmitted by domesticated cats. Cowpox infection usually confers immunity to smallpox, because of the similarity of the variola and vaccinia viruses. Also called cat pox. See also smallpox, vaccinia.

cowpox
a benign, contagious disease of cows characterized by the appearance of pox lesions on the teat and udder skin. The causative virus is in the genus Orthopoxvirus. Typical lesions are a patch of erythema, then a papule, followed by a vesicle, then a pustule and finally a scab. The disease is transmissible to humans and is now rare.

cowpox virus
a poxvirus which is antigenically distinct from vaccinia virus and pseudocowpox virus. The characteristics of the virus are otherwise identical with the vaccinia virus. See also vaccinia.


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DNA virus isolates from tissue culture samples used to test GreeneChip performance Virus Genus Sealpoxvirus 1 * Parapoxvirus Pseudocowpox virus ([dagger]) Parapoxvirus Orf virus ([dagger]) Parapoxvirus Cowpox virus ([dagger]) Orthopoxvirus Human herpesvirus ([dagger]) * Simplexvirus Gallid herpesvirus 1 ([dagger]) Iltovirus Human adenovirus E (HAdV-4) ([double dagger]) Mastadenovirus Human adenovirus C (HAdV-5) ([double dagger]) Mastadenovirus * University of Florida, Gainesville, FL, USA.
In 1796, an English doctor discovered that patients who had recovered from a cattle disease called cowpox were immune to the more dangerous smallpox.
The new vaccine, called MVA85A by researchers, consists of weakened cowpox virus that has been genetically engineered to make a protein normally found on the surface of M.
 
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