cowpox


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to cowpox: cowpox vaccine

cowpox

 [kow´poks]
a mild pustular eruption affecting milk cows, usually confined to the udder and teats, caused by the vaccinia virus, and transmissible to humans. Edward Jenner, in the 18th century, discovered that cowpox could be transmitted to humans who milked or tended cattle, and also noted that persons who contracted it in this way seldom contracted smallpox. This discovery led to vaccination against smallpox.

cowpox

/cow·pox/ (kou´poks) a mild eruptive disease of milk cows, confined to the udder and teats, due to cowpox virus, and transmissible to humans.

cowpox

(kou′pŏks′)
n.
A mild contagious skin disease of cattle, usually affecting the udder, that is caused by a virus and characterized by the eruption of a pustular rash. When the virus is transmitted to humans, as by vaccination, it can confer immunity to smallpox. Also called vaccinia.

cowpox

[kou′poks]
Etymology: AS, cu + ME, pokkes
a mild infectious disease characterized by a pustular rash, caused by the vaccinia virus. Animals that carry the vaccinia virus are cows, cats, and rodents. Human cases are usually rare. Transmission to humans can occur during the milking of a cow with active lesions on the udder and teats, but the disease is usually transmitted by domesticated cats. Cowpox infection usually confers immunity to smallpox, because of the similarity of the variola and vaccinia viruses. Also called cat pox. See also smallpox, vaccinia.

cowpox

A mild disease of cows' udders and teats that can be transmitted to people, doing manual milking. It causes skin blisters and confers immunity against SMALLPOX-a somewhat academic consideration now that this disease has been eradicated. Jenner's observations on cowpox led to vaccination and the science of immunology. (Edward Jenner, 1749–1823, English physician).

cowpox

a benign, contagious disease of cows characterized by the appearance of pox lesions on the teat and udder skin. The causative virus is in the genus Orthopoxvirus. Typical lesions are a patch of erythema, then a papule, followed by a vesicle, then a pustule and finally a scab. The disease is transmissible to humans and is now rare.

cowpox virus
a poxvirus which is antigenically distinct from vaccinia virus and pseudocowpox virus. The characteristics of the virus are otherwise identical with the vaccinia virus. See also vaccinia.
References in periodicals archive ?
Vaccinia and cowpox seldom spread from person to person.
Comparison and phylogenetic analysis of cowpox viruses isolated from cats and humans in Fennoscandia.
Scientists later discovered that it worked by stimulating the body to produce antibodies, agents that fight specific "invaders"--in this case, the cowpox and smallpox viruses.
Alternatively, this patient might have been infected by other animals; he reported regular, close contact with horses and domestic cats that go outdoors, and horses and cats are known to transmit cowpox viruses to humans (12).
1] Nonstandard abbreviations: VAR, variola major virus; MPV, monkeypox virus; CML, camelpox virus; VAC, vaccinia virus; CPV, cowpox virus; FRET, fluorescence resonance energy transfer; HA, hemagglufinin gene; ENIVD, European Network for the Diagnosis of Imported Viral Diseases; and geq, genome equivalents.
Guarnieri's bodies in vesicular scrapings can be seen with Gispen's modified silver stain, but the inclusions do not differentiate between cowpox, monkeypox, and smallpox.
An alignment was created from complete genome sequences from 11 MPXV isolates and cowpox virus Grisham (CPXV_GRI) by using MAFFT version 6 (http://mafft.
The vaccinia virus in Dryvax has an obscure origin; it is based primarily upon the cowpox virus and may represent a re-assortment of smallpox and cowpox viruses.
Smallpox was a serious problem in the 18th century, and Jenner had been impressed by the fact that people suffering an attack of cowpox, a relatively harmless disease that could be contracted from cattle, could not be contaminated by smallpox.
Related studies also indicated that the Hemopurifier was effective in removing other smallpox related viruses, including cowpox and mousepox.
When examining skin lesions on llamas, viral diseases to consider as differential diagnoses include vesicular stomatitis, rabies, poxvirus (contagious ecthyma and cowpox virus [CPXV]) (2), foot-and-mouth disease, bluetongue, and mucocutaneous fibropapillomas (3).
Furthermore, the RAMP Pox Test was also shown to recognize monkeypox and cowpox, the only orthopox viruses in addition to variola and vaccinia known to cause human infection.