With this novel technology, Avila demonstrated that AVL-181 successfully blocked HCV protease enzyme activity and that the HCV protease target was covalently
bonded and silenced in vivo.
This enzyme expression converts AF to metabolites that are covalently
bound to DNA.
The '078 patent purports to cover methods of dimerizing and activating the EPO receptor using covalently
linked peptide monomers which do not activate the EPO receptor unless dimerized.
Thermosets do have a performance advantage in that, because they are covalently
bonded into a network structure, imposed forces are widely distributed throughout the part, and creep is not as prevalent a problem as it is with thermoplastics.
Mass spectrometry showed that this DNA contains only trace amounts of free arsenate and no detectable covalently
bound arsenate," they concluded.
Captivate[TM] particles consist of a magnetite core enveloped by a ceramic zirconium oxide coating, to which carefully selected and purified antibodies to surface components of the target microorganism are covalently
Other admirable qualifies include the wherewithal to covalently
bind nucleic acid samples to membranes in less than 30 seconds (240 times faster than vacuum-oven baking, according to the firm), and enhance sample visibility on autoradiograms by up to 445 percent.
The active toxic A-chain is covalently
linked via a disulfide bond to the sugar binding B-chain, this bond being biologically important as the individual chains are biologically inactive.
Chemists, materials scientists and engineers, and other researchers report recent findings regarding polymeric biomaterials, including interpenetrating polymer networks (IPM), a form in which two or more networks are at least partially interlaced but not covalently
Then, an anti-MUC1 monoclonal antibody entitled PR81 was attached covalently
to the surface of the nanoparticles in order to effectively deliver the mentioned drug to the cancer cells.
The arsenic disappeared, indicating it wasn't covalently
bound to DNA.
When the electron-accepting NDI chromophore is covalently
bonded to an electron-donating group such as DAN the resulting complex tends to facilitate charge-transfer (C-T) induced donor-acceptor (D-A) stacking.