cotyledonosis

cotyledonosis

poisoning of livestock in southern Africa by plants in the genera Tylecodon and Cotyledon spp containing cumulative bufadienolide cardiac glycosides. Clinical signs include exercise intolerance, paresis, paralysis, torticollis, paralysis of the lower jaw and tongue, dysphagia, drooling of saliva, abdominal pain, convulsions and death within a few hours. No significant necropsy lesions. Secondary poisoning occurs in dogs and humans who eat meat from diseased animals. Called also krimpsiekte.