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cosyntropin

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cosyntropin /co·syn·tro·pin/ (ko-sin-tro´pin) a synthetic polypeptide identical with a portion of corticotropin, having its corticotropic activity but not its allergenicity; used in the screening of adrenal insufficiency on the basis of plasma cortisol response.
co·syn·tro·pin (ksn-trpn)
n.
A synthetic corticotropin. Also called tetracosactide.

cosyntropin
[kō`sintrop′in]
a synthetic form of adrenocorticotropic hormone that is used in the diagnosis and treatment of adrenal hypofunction disorders such as Addison's disease to determine if the disorder is primary (adrenal dysfunction) or secondary (hypothalamic-pituitary axis dysfunction).

cosyntropin [ko″sin-tro´pin]
a synthetic corticotropin used in the screening of adrenal insufficiency on the basis of plasma cortisol response after intramuscular or intravenous injection.

cosyntropin
a synthetic corticotropin used in the screening of adrenal functional capacity on the basis of plasma cortisol response after intramuscular or intravenous injection. Called also tetracosactrin.


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The researchers found that all patients showed an adequate adrenal response to cosyntropin before and after budesonide therapy.
A work-up for infection, malignancy, and rheumatologic conditions was negative, and primary adrenal insufficiency was ruled out based on the findings of a cosyntropin stimulation test.
Adrenal insufficiency was excluded with a cosyntropin stimulation test, with a normal increase in serum cortisol from a baseline of 13 [micro]g/dL to 24 [micro]g/dL.
 
 
 
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