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cosmid

   Also found in: Dictionary/thesaurus, Wikipedia, Hutchinson 0.01 sec.
cosmid
a class of plasmid-based vectors carrying the bacteriophage λ cos sequences required for packaging of DNA into phage particles. Used for cloning large DNA fragments (up to 45 kilobases). Recombinant molecules constructed using cosmids are incorporated into bacteriophage using in vitro packaging extracts and introduced with high efficiency into Escherichia coli.


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Created with DNA from a bacteriophage (a virus that infectsbacteria) combined with genetic material called a cosmid from the common bacterium Escherichia coli, the shuttle phasmid can infect mycobacteria and grow in E.
erythraea was derived from 256 canonically ordered cosmid clones representing a circular genome of 8.
 
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