cosegregation

cosegregation

(kō-sĕg-grĕ-gā-shun),
A conceptual term often used to mean "tracking" (for example, an allele cosegregating or "tracking" with a disorder).
References in periodicals archive ?
As expected, cosegregation analysis of the mutations revealed that each parent was a carrier of one alteration.
Currently, such supporting evidence includes detecting a recurring de novo mutation in a gene with a deleterious effect on the encoded protein in similarly affected patients, showing cosegregation in family members, and/or providing compelling evidence of the underlying biology and mechanism.
All SGI ROTAV strains were associated with the P[6] or P[4] genotype, and all SGII ROTAV strains were associated with P[8], demonstrating a gene-dependent cosegregation pattern.
Unfortunately, no relatives were available to perform cosegregation analysis.
Familial predisposition and cosegregation analysis of adult obstructive sleep apnea and the sudden infant death syndrome.
Iodide organification defects resulting from cosegregation of mutated and null thyroid peroxidase alleles.
Brassicaceae) analysed by a cosegregation of phenotypic characters (QTL) and molecular markers.
The investigators noticed cosegregation of dyslexia, defined by oral reading ability at least two years below expected grade level, and a cytogenetic polymorphism at the top of the acrocentric chromosome 15 in eight families selected on the basis of apparent autosomal dominant transmission of the disorder.
Cosegregation of a novel Bartonella species with Borrelia burgdorferi and Babesia microti in Peromyscus leucopus.
Characterization of five new mutants in the carboxyl-terminal domain of human apolipoprotein E: no cosegregation with severe hyperlipidemia.
henselae DNA has been amplified, and that serologic and molecular evidence suggests cosegregation of Bartonella spp.
In two families, cosegregation with the disease could not be assessed because of a lack of available DNA samples.