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corticotropin-releasing hormone

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia, Hutchinson 0.04 sec.
corticotropin-releasing hormone
n. Abbr. CRH
A hormone produced by the hypothalamus that stimulates the anterior pituitary gland to release adrenocorticotropic hormone. Also called corticoliberin, corticotropin-releasing factor.

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One likely messenger is corticotropin-releasing hormone (CRH), ordinarily a stress hormone secreted by the brain but produced in pregnancy by the baby's placenta.
That finding suggests that the entire "fight-or-flight" stress-response system based on corticotropin-releasing hormone (CRH) dates back to a common ancestor of vertebrates and insects.
The PVN of the hypothalamus has a large number of corticotropin-releasing hormone neuronal cell bodies and receives rich noradrenergic innervation from the brainstem, through the ventral noradrenergic bundle (Petrusz and Merchenthaler 1992).
 
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