corticotroph


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corticotroph

 [kor´tĭ-ko-trōf]
a type of acidophil found in the anterior lobe of the pituitary gland that secretes corticotropin; it is synthesized as a large prohormone containing both corticotropin and β-lipotropin.

cor·ti·co·troph

(kōr'ti-kō-trof),
A cell of the adenohypophysis that produces adrenocorticotropic hormone (ACTH).

corticotroph

/cor·ti·co·troph/ (kor´tĭ-ko-trōf) an acidophil of the adenohypophysis that secretes corticotropin.

corticotroph

[kor′tikōtrof′]
a small, irregularly stellate, acidophilic cell of the adenohypophysis, having small, sparsely distributed secretory granules and secreting adrenocorticotropic hormone and beta-endorphin. Also called corticotrope, corticotropic cell.

cor·ti·co·troph

(kōr'ti-kō-trōf)
A cell of the adenohypophysis that produces adrenocorticotropic hormone.
References in periodicals archive ?
Corticotroph adenomas (~10% of pituitary tumors) stain immunopositive for ACTH.
In our patient, inappropriate secretion of ACTH from a corticotroph adenoma or hyperplasia in a brief period may be described by inappropriate replacement with synthetic glucocorticoid.
Histological and immunohistochemical findings led to identification of corticotroph adenocarcinoma in the pituitary gland.
Proliferation of lactosomatotroph GH3 and somatotroph MtT/S rat pituitary cells as well as of corticotroph AtT20 mouse pituitary cells was inhibited by curcumin in monolayer cell culture and in colony formation assay in soft agar.
It also acts on other central and peripheral receptors and exhibits other actions, including stimulation of lactotroph and corticotroph secretion; it also influences gastroenteropancreatic functions and has orexigenic, metabolic, cardiovascular, and antiproliferative effects (60-62).
Invasion is characteristic of thyrotroph adenomas, silent corticotroph adenomas, and the unusual plurihormonal silent subtype 3 adenomas.
Corticotroph Tumor Progression after Adrenalectomy in Cushing's Disease: A Reappraisal of Nelson's Syndrome.
PPAR-gamma ligands inhibit in vitro and in vivo corticotroph tumor growth by increasing the apoptotic pituitary corticotroph tumor cells.
The hypothalamus produces corticotropic hormone, which stimulates corticotrophs to release ACTH, which then stimulates the adrenal cortex to produce and release cortisol and androgens.
Cytochemical identification of human and murine pituitary corticotrophs and somatotrophs as APUD cells.
It is possible that their hypocortisolic state is related to prolonged compression and irreversible damage to the corticotrophs.