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Patients who must take exogenous adrenal corticosteroids to supplement a deficit in endogenous cortisol or as a treatment for metastatic breast cancer should be thoroughly instructed in self-medication. Their needs are somewhat similar to those of the insulin-dependent diabetic patient. They should know the prescribed dosage and basic therapeutic action of the oral corticosteroid preparation they are taking and should be aware of the importance of taking the medication at the same time every day. The medication should never be discontinued abruptly for any reason. It is advisable that the patient carry an extra prescription when traveling, in case the supply is used up before returning home. These patients also need to wear some form of medical identification so that all health care professionals with whom they come in contact will know that they are receiving hormones of this kind. This includes dentists, oral surgeons, emergency department personnel, and others who might not be familiar with the patient's medical history.
corticosteroid/cor·ti·co·ster·oid/ (-ster´oid) any of the steroids elaborated by the adrenal cortex (excluding the sex hormones) or any synthetic equivalents; divided into two major groups, the glucocorticoids and mineralocorticoids; used clinically for hormonal replacement therapy, for suppression of ACTH secretion, as anti-inflammatory agents, and to suppress the immune response.
corticosteroidClinical pharmacology Any of the steroids elaborated by the adrenal cortex–excluding the sex hormones of adrenal origin in response to the release of ACTH by the pituitary gland, to any of their synthetic equivalents or to angiotensin II; corticosteroids are used to manage arthropathies, inflammation, CA
Synonym(s): corticoid (3) .
corticosteroida steroid hormone of the adrenal cortex.
corticosteroidsynthetic analogue of adrenal corticosteroid taken systemically (e.g. prednisolone), injected into a joint (e.g. hydrocortisone) or applied topically (e.g. HC45) to reduce acute inflammation; used parenterally as replacement therapy in Addison's disease or following adrenalectomy
topical corticosteroid Table 1
Mild with anti-microbial
|e.g.: Hydrocortisone 0.5-1%|
e.g.: Canesten HC, Daktacort, Fucidin H; Synalar 1:10
|Moderate||e.g.: Betnovate RD; Eumovate, Haelan; Synalar 1:4|
|Moderate with anti-microbial||e.g.: Trimovate|
|Moderate with urea||e.g.: Calmurid HC|
|Potent||e.g.: Betamethasone valerate 0.1%; Betnovate; Synalar|
|Potent with anti-microbial||e.g.: Aureocort; Betnovate-C; Tri-Adcortyl; Synalar C|
|Potent with salicylic acid||e.g.: Diprosalic|
Very potent with anti-microbial
Mild and moderate preparations have few side effects; Care is required in the use of potent or very potent topical corticosteroids and absorption through the skin can cause Cushingoid symptoms and adrenal cortex suppression; absorption is greatest through raw skin, or where larger areas of skin are treated.
Patient discussion about corticosteroid
Q. I received a corticosteroid injection in my left knne th A.M. Knee is all stiff & swollen. Is this normal?