cornoid lamella

cor·noid la·mel·la

a narrow vertical column of parakeratosis in the epidermal stratum corneum; characteristic of porokeratosis.
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Porokeratosis is a specific keratinization disorder that manifests clinically as well-demarcated annular or linear keratotic plaques of various sizes and forms and with distinguished histology showing cornoid lamella, which is a column of closely packed parakeratotic cells extending through the stratum corneum.
Keywords: porokeratosis of Mibelli, onychodystrophy, cornoid lamella
Porokeratosis is a well-known keratinization disorder where cornoid lamella is characteristically seen.
Skin biopsy showed column of parakeratosis suggestive of Cornoid lamella and focal loss of granular layer beneath the porokeratotic column.
Biopsy of this area showed a cornoid lamella, which is seen in porokeratosis.
Pathologically, porokeratosis is characterized by a column of parakeratotic cells, called the cornoid lamella.
INTRODUCTION: Porokeratosis is an autosomal dominant genodermatosis with variable penetrance, characterized by a clonal disorder of keratinization with one or more atrophic patches surrounded by a clinically and histologically distinctive hyperkeratotic ridge like border called the cornoid lamella.
Cornoid lamella, a histopathological marker, results from abnormal proliferation of keratinocytes.
The diagnosis is based on the histopathologic finding of a cornoid lamella, absence of a granular layer, and often a thin epidermis.
It is now thought that the ring-like cornoid lamella the hallmark of porokeratosis may be located in the interadnexal epidermis acrosyringium of eccrine sweat duct or within the infundibulum of pilar apparatus.
1 Actinic porokeratosis appears as double edged typical lesion with atrophic centre over sun exposed areas of body and on histopathology a characteristic cornoid lamella is found .
Porokeratosis is an inherited disorder of keratinization characterized clinically by skin lesions with distinctive hyperkeratotic ridge-like border and histologically by presence of cornoid lamella.