Diabetes mellitus invariably impairs the corneal sensitivity
in diabetic patients and approximately 20% of patients suffer to some degree of decreased corneal sensations5.
The corneal sensitivity
, number of corneal nerve fibers, and contents of vascular endothelial growth factor (VEGF)-B and various neurotrophic factors such as nerve growth factor (NGF) and glial cell line-derived neurotrophic factor (GDNF) in corneal tissue of four groups were observed.
Multiple studies have revealed the influence of diclofenac and ketorolac in fading pain along with corneal sensitivity
consequent to corneal abrasion.
14) Clinical manifestations include opacification of the central or midperipheral cornea, dense arcus senilis, reduced corneal sensitivity
, and recurrent corneal erosion.
has alert function for possible injuries or diseases (BROOKS et al.
05), but VisuMax offered faster recovery of corneal sensitivity
and tearfilm break-up time.
Chronic corneal ulceration, entropion, decreased corneal sensitivity
and some infectious agents like feline herpes virus-1 have been considered as triggering factors in formation of corneal sequestrum (Williams and Kim, 2009).
13-21) This denervation of the cornea during refractive surgery is the cause of a decrease in corneal sensitivity
following the procedure.
The effects of the topical administration of non-steroidal anti-inflammatory drugs on corneal epithelium and corneal sensitivity
in normal subjects.
Neurotrophic Keratopathy (NK) is a serious degenerative disease of the corneal epithelium (the outside layer of the eye) and a reduction in corneal sensitivity
or complete corneal anesthesia is the hallmark of this disease and is responsible for producing corneal ulceration, perforation, pain and impaired vision.
To evaluate corneal sensitivity
(recorded as present, absent, or diminished) before application of topical anesthetic, a wisp of cotton formed from a cotton-tipped applicator was used to gently touch the central cornea.
after topical bromofenac sodium eye drop instillation.