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corepressor

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corepressor /co·re·pres·sor/ (ko″re-pres´er) in genetic theory, a small molecule that combines with an aporepressor to form the complete repressor.
co·re·pres·sor (kr-prsr)
n.
A substance that combines with and activates a genetic repressor, thus preventing gene transcription and inhibiting protein synthesis.

corepressor [ko″re-pres´ser]
a small molecule that combines with a protein aporepressor molecule to form an active substance, which then binds to an operator gene and inhibits the synthesis of an enzyme.

corepressor
a substance (e.g. the product of a metabolic pathway) that activates a repressor by combining with it.


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1 his tone deacetylase complex; transcription corepressor activity corepressor activity 215378_at Ankyrin repeat and KH domain 5q31.
Weaver's team found that cancer cells grown in a 3-D environment had higher levels of a protein called nuclear receptor corepressor 2 (N-CoR2) than cells in flat dishes.
Corepressor requirement and thyroid hormone receptor function during Xenopus development.
 
 
 
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