cord blood transplantation

cord blood transplantation

the removal of blood from the umbilical cord of a fetus or its placenta for the treatment of blood diseases. Cord blood transplantation has been performed successfully in patients with leukemia, aplastic anemia, Fanconi's anemia, immunodeficiency, and genetic and metabolic disorders.
References in periodicals archive ?
The financing also included Casdin Capital and other crossover investors, as well as Be The Match BioTherapies, a subsidiary of National Marrow Donor Program (NMDP)/Be The Match, the world's leading organisation focused on saving lives through bone marrow and umbilical cord blood transplantation.
Varicella-zoster virus encephalitis in a patient undergoing unrelated cord blood transplantation for myelodysplastic syndrome-overt leukemia.
After written informed consent of the parents, autologous cord blood transplantation was prepared to take place at the Department of Pediatrics, Ruhr-University Bochum, according to the German legal requirements (AMG [section]41(2) [BGBl.
Fate Therapeutics president and chief executive officer Christian Weyer stated that for many severe inherited metabolic disorders, including those with central nervous system involvement, cellular enzyme replacement through unrelated donor cord blood transplantation has emerged as a potentially transformative therapeutic intervention.
Key words: Childhood, hematopoetic stem cell transplantation, cord blood transplantation
Umbilical cord blood transplantation for children with thalassemia and sickle cell disease.
The approach using NiCord, as a single stem cell graft, has the potential to broaden accessibility, reduce toxicity and improve the clinical and economic outcomes of cord blood transplantation.
They describe stem cells found in amniotic fluid, the clinical practice of cord blood transplantation, hematopoietic stem cell development in the placenta and transplantation, uses for preventing and treating complications after transplantation, cord tissue/Wharton's jelly-derived stem cells, immunogeniocity and immunomodulatory effects, uses in treating and preventing graft-versus-host disease in hematopoietic transplantation, the amnion and regenerative medicine applications, the role of stem cells in regenerative medicine, the amniotic membrane, and fetal stem cells in maternal circulation.
Cord Blood Transplantation Trends: Age of Recipient, Disease Classes Addressed
The only cell functionality test presently used in this field, especially for umbilical cord blood transplantation, is the colony-forming unit (CFU) assay, which is subjective, non-validated and has been used since the early 1970s.
Demand for cord blood could increase or decrease depending on a number of variables, such as whether new research identifies ways to increase the benefits of cord blood or conversely, the development of alternative treatments to cord blood transplantation.