copy number


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copy number

  1. the number of copies of a particular PLASMID per CHROMOSOME present in a CELL.
  2. the number of copies of a GENE in the GENOME of an ORGANISM.

copy number

the number of plasmid or other DNA molecules in a cell.
References in periodicals archive ?
The new Nexus Copy Number for Affymetrix software offers researchers a version of the Nexus Copy Number software that is easier to access and has been specifically tailored for Affymetrix' assays.
This generates sufficient data points to simultaneously identify fetal copy number at multiple chromosomes using cfDNA.
In this article, we report the use of shotgun MPS to obtain a noninvasive, genomewide view of cancer-associated copy number variations and mutations in DNA in plasma.
The new analytic method, devised by Cold Spring Harbor Laboratory (CSHL) Professor Michael Wigler and colleagues, features a process called single cell sequencing (SNS), which enables accurate quantification of genomic copy number within a single cell nucleus.
falciparum multidrug resistance 1 (pfmdr1) gene copy number is associated with an 8-fold risk for artesunate--mefloquine failure in western Cambodia (6).
TWO men facing terrorism charges walked free yesterday after concerns over low copy number DNA testing.
Makers claim it will be the biggest development in DNA analysis and interpretation since the Forensic Science Service conceived and introduced Low Copy Number, which enabled a match to be found from a minute sample of cells.
NanoString's suite of new products accelerates sample throughput for validation studies, enhances copy number studies using FFPE archival samples, and provides the latest content for human microRNA assays.
This sub-specialty of NGS analysis carries significant value for identifying many conditions where structural variants, such as copy number variations (CNVs), are important yet go unnoticed because most software tools are not able to recognize them.
Increases in the KLK6 gene copy number have been previously reported in OCa (6), and the KLK locus (19q13.
Seemingly similar cells, especially cancer cells, often have significantly different genetic mutations and therefore detailed knowledge of these mutations, called copy number variations (CNVs), in individual cells can point to specific treatment regimens, said the study published in the journal Nature Methods.
Current diagnostic testing for a large number of cytogenetic referrals involves the assessment of copy number imbalances using array comparative genomic hybridisation (array CGH).