endpoint in EU and Japan; key secondary endpoint In other regions.
The cumulative risk of the coprimary
end-point, peptic ulcer disease, was 3% in both groups (risk ratio, 0.
endpoint in European Union and Japan; key secondary endpoint in other regions.
A critical assessment of composite and coprimary
endpoints: A complex problem.
All 4 coprimary
objectives measured improved with treatment compared with mean baseline levels: percentage of parabasal cells in treated participants decreased by 27.
One area of vigorous discussion remaining unresolved at the end of the morning's talks was whether a functional assessment, in addition to neuropsychological testing, should be a required coprimary
However, during the course of the study, "entrainment"--which involves urine tests that measure biochemical correlates of circadian rhythm--was added as a coprimary
endpoints were disease-free survival (DFS) at 2.
endpoints included change from baseline in urinary incontinence episodes per day at week 12 and the proportion of patients reporting improvement or great improvement in their urinary incontinence (UI) at 12 weeks.
Improvements in global function were also evaluated as a coprimary
study endpoint and were not found to achieve statistical significance, as evaluated by changes from baseline in the Clinician's Interview-Based Impression of Change Plus Caregiver Input scores (4.
case was defined as a varicella case in a student with onset of rash [less than or equal to] 10 days after occurrence of a primary case in the same classroom.
The studies are evaluating as coprimary
endpoints the effect of Ostarine[TM] versus placebo on total lean body mass (muscle) assessed by dual x-ray absorptiometry (DXA) and on physical function assessed by the Stair Climb Test at three months.