controlled trial

controlled trial

Clinical research A clinical study in which one group of participants receives an experimental drug while the other receives either a placebo or an approved–'gold standard' therapy. See Blinding, Double-blinded.
References in periodicals archive ?
Reducing SFA consumption is recommended to reduce CHD, but there is little strong randomised controlled trial (RCT) evidence of CHD events and few guidelines for specific SFA substitutes.
The article speaks of the initial pilot study in dyslexia being a double-masked, placebo controlled trial and that was most certainly not the case and it was never represented as such.
Edwards describes early trials and the controversy surrounding them, the fates of such trials as the evaluation of raw pancreas therapy and light therapy, the controversies of serum therapy for pneumonia from 1929 to 1934, the strategies of Almroth Wright and Bradford Hill to capture the nomenclature of controlled trials, and in a fascinating conclusion, what is controlled about the current controlled trial.
Terblanche and colleagues investigated the use of adjunctive corticosteroid treatment of clinical PCP in infants in a randomised controlled trial.
A new randomised controlled trial of the effectiveness of an intensive exercise program immediately after hospital has recently been published (Bulthuis 2007), and new studies examining the cost effectiveness of such programs should be done.
This randomised, controlled trial evaluated the comprehensibility of instructions in different formats on what to do when oral contraceptive pills are missed.
An intervention is most acceptable when it has been shown in a randomized controlled trial to be better able to accomplish a predetermined outcome than is some other intervention or no intervention at all (placebo).
Haidet, Richards, Morgan, Wristers, and Moran (2003) conducted a controlled trial of self-directed learning versus lecture with medical residents studying evidence based medicine.
Household based treatment of drinking water with flocculant-disinfectant for preventing diarrhea in areas with turbid source water in rural western Kenya: cluster randomized controlled trial.
1) In a randomized controlled trial conducted in Philadelphia, participants in a skills-based STD prevention intervention reported less unprotected sex one year later than did a control group, who received a general health promotion intervention.
Severity of depression in the STAR-Center study and the randomized controlled trial were similar.
But in 1996, when new laparoscopic and balloon procedures were developed, scientists believed it was time to test these operations in a randomized, controlled trial.

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