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controlled clinical trial

   Also found in: Acronyms 0.03 sec.
controlled clinical trial,
n a research strategy that calls for two samples: an experimental sample of patients receiving a pharmaceutical, and a second sample of control patients receiving a placebo. Neither the patient nor the researcher knows which is receiving the pharmaceutical and which the placebo.

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The goal of this proof of concept, internally controlled clinical trial was to evaluate the safety and ability of TRCs -- a proprietary autologous bone marrow-derived stem cell product -- to increase bone height in the posterior maxilla (upper jaw) of 5 patients, who had severe bone loss in the region and minimal residual bone remaining.
This Phase I, randomized, prospective, controlled clinical trial will compare the effect of surgery to lengthen the Achilles tendon with the foot in a cast to using a cast alone.
A year-long, double-blind, randomized, controlled clinical trial conducted in Germany compared the efficacy and safety of Vertigoheel to those of
 
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