contact inhibition

inhibition /in·hi·bi·tion/ (in″hĭ-bish´un)

1. arrest or restraint of a process.

2. in psychoanalytic theory, the conscious or unconscious restraining of an impulse or desire.

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competitive inhibition  inhibition of enzyme activity in which the inhibitor (a substrate analogue) competes with the substrate for binding sites on the enzymes.

contact inhibition  inhibition of cell division and cell motility in normal animal cells when in close contact with each other.

endproduct inhibition , feedback inhibition inhibition of the initial steps of a process by an endproduct of the reaction.

noncompetitive inhibition  inhibition of enzyme activity by substances that combine with the enzyme at a site other than that utilized by the substrate.

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contact inhibition

n.

Cessation of replication of dividing cells that come into contact.

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inhibition

arrest or restraint of a process.

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competitive inhibition

inhibition of enzyme activity by an inhibitor (a substrate analog) that competes with the substrate for binding sites on the enzymes.

contact inhibition

inhibition of cell division and cell motility in normal animal cells when in close contact with each other.

end-product inhibition

see feedback inhibition (below).

feedback inhibition

a common way of regulating enzyme activity in which the reaction product (or in the case of a biosynthetic pathway, the product of the reaction sequence) inhibits the enzyme activity. Called also end-product inhibition.

neurological inhibition

the intermittency of transmission of nervous impulses depends on variations in the balance between excitation and inhibition, the latter being either pre- or postsynaptic.

noncompetitive inhibition

inhibition of enzyme activity by substances that combine with the enzyme at a site other than that utilized by the substrate.