In contrast, the pathologic findings of constrictive bronchiolitis
can be easy to miss, in both mild disease when findings are subtle and even in severe disease when the airway is obliterated.
(CB) is a lung disease characterized by fixed airways obstruction and fibrosis of the distal airways or bronchioles, with extrinsic narrowing or obliteration of the bronchiolar lumen.
Although inhaled steroids and mucus clearance therapy improved her cough, her dyspnea continued to worsen; an open lung biopsy was performed, which revealed constrictive bronchiolitis
(the histopathologic correlate of obliterative bronchiolitis) with both narrowed and obliterated airways with surrounding fibrous tissue and a variable mixed chronic inflammatory cell infiltrate.
Then the physician is in the challenging position of having to decide whether to send someone for a surgical lung biopsy to evaluate the possibility of constrictive bronchiolitis
because you can't make that diagnosis without a biopsy," Dr.
Unfortunately, veterans returning from the current wars are unable to obtain service connection for such health problems as constrictive bronchiolitis
, a rare disease caused by exposure to an environmental toxin, as well as cancer, heart disease and most respiratory illnesses" National Service Director Garry T.
Some soldiers serving in the Middle East who develop difficulty breathing--but whose chest X-rays show nothing out of the ordinary--have constrictive bronchiolitis
, a kind of lung damage virtually unknown in young adults.
The ex vivo bronchiolar smooth muscle contraction causes prominent narrowing of the bronchiolar lumen, which may give a false impression of constrictive bronchiolitis
or other small airway diseases, including asthma.
The clinical illness constrictive bronchiolitis
is described in a
should be considered in all returning veterans who report exercise limitations due to dyspnea, according to the results of a case series.
A dreaded form of small airways disease in RA is irreversible, constrictive bronchiolitis
, which is often diagnosed before a biopsy is performed because of characteristic findings on pulmonary function tests and evidence of bronchiolar disease, demonstrable by the presence of a mosaic pattern (mosaic perfusion) on high-resolution computed tomography.
is a lung disease characterized by fixed airways obstruction and fibrosis of the distal airways or bronchioles, with extrinsic narrowing or obliteration of the bronchiolar lumen.
Primary bronchiolitides are additionally challenging as the histologic findings are often extremely subtle, particularly those of constrictive bronchiolitis