with constitutive resistance
present in vitro resistance to all macrolides, lincosamides, and type B streptogramins.
While constitutive resistance
can be easily detected on routine antimicrobial sensitivity testing on disc diffusion, the true picture of inducible MLSB phenotype is masked, i.
Bioassay versus chemical assay: measuring the impact of induced and constitutive resistance
on herbivores in the field.
Only 4 of the 46 isolates (8%) expressed constitutive resistance
Physicians should make sure their microbiology lab is testing for both inducible and constitutive resistance
to clindamycin when they send samples for susceptibility testing, Dr.
90] Range Constitutive resistance
(n =21) Erythromycin A 512 >512 16 >512 Clindamycin 128 256 32-512 Telithromycin 0.
Genotypes of soybeans are known to vary in their constitutive resistance
to disease, fungi, nematodes, and insect herbivores.
The suggestion that fungal endophytes mediate inducible responses is an extension of the defensive mutualism hypothesis (above), which as currently articulated, proposes that endophytes provide constitutive resistance
to herbivores (Clay, 1988, 1990).
aureus isolates with constitutive resistance
show resistance to erythromycin and clindamycin and isolates with inducible resistance are resistant to erythromycin, but appear susceptible to clindamycin.
1%) isolates have had constitutive resistance
mechanism and only 33 (26.
In constitutive resistance
, the microbe is dearly resistant to both erythromycin and clindamycin, and the lab will be able to pick this up using any susceptibility test, she explained at the meeting, which was also sponsored by the University of Colorado.
With respect to the constitutive resistance
against an insect herbivore, our results support the CNB hypothesis; the larvae of E.