constant domains

constant domains

the C-terminal regions of heavy and light chains of immunoglobulins; they contain the amino acid sequences that are similar in different antibodies of the same class. See also cH domains; cL domain.
References in periodicals archive ?
These heavy-chain antibodies contain a single variable domain (VHH) and two constant domains (CH2 and CH3).
While there is more than 90% sequence homology between the constant domains of [[gamma].
Peptibodies are engineered therapeutic molecules that can bind to human drug targets and contain peptides linked to the constant domains of antibodies.

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