consensus sequence

consensus sequence

[kənsen′səs]

a sequence of nucleotides or amino acids similar or identical between regions of homology in different but related DNA, RNA, or protein sequence.

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sequence

the order in which monomers occur in polymeric molecules; the order of amino acids in a polypeptide chain or of nucleotides in nucleic acid.

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autonomously replicating sequence

usually plasmids that replicate independently of chromosomal DNA.

coding s's

sections of DNA which code for the amino acids of a protein.

consensus sequence

a sequence of nucleotides that is always present in a large set of independently determined sequences. See also box.

enhancer sequence

in DNA transcription, an upstream cis-acting DNA sequence that enhances expression of a particular gene and forms part of a complex array of upstream sequences that control gene expression.

expressed s's

in eukaryotic pre-messenger RNA the noncoding sequences, also called intervening sequences or introns, are removed in the nucleus; the mRNA is transported to the cytoplasm where the exons are translated to a protein.

intervening sequence

see intron.

palindromic sequence

see palindrome.

signal sequence

a collection of hydrophobic amino acid residues at the amino terminus of secretory or integrated membrane proteins that direct the protein to cell membranes, particularly endoplasmic reticulum where the proteins are modified, e.g. glycosylated, and the signal sequence is removed prior to secretion or integration of the protein into the lumen of the endoplasmic reticulum.

temporal sequence

in protein synthesis, is from the amino to the carboxyl end.