GJA4

(redirected from connexin 37)

GJA4

A gene on chromosome 1p35.1 that encodes an alpha chain of the gap junction protein family or connexins.
 
Molecular pathology
GJA4 mutations are linked to atherosclerosis and an increased risk of myocardial infarction.
References in periodicals archive ?
Connexin 37 seems to link the developing eggs, or oocytes, and the surrounding cells, called granulosa cells.
The finding confirms previous suspicions that connexin 37 forms a channel through which ions, metabolites, and signaling molecules can pass.
When connexin 37 is absent, the whole process falls apart," says Paul.
The steps of the failed developmental process offer clues to the messages that the connexin 37 channels convey.
John Eppig, a reproductive biologist at Jackson Laboratories in Bar Harbor, Maine, calls the study "exciting" but cautions that scientists don't think connexin 37 carries all the communications between the oocyte and granulosa cells.