GJB1

(redirected from connexin 32)

GJB1

A gene on chromosome Xq13.1 that encodes a beta chain of the gap junction protein family or connexions.

Molecular pathology
GJB1 mutations cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy.
References in periodicals archive ?
Following treatment of cells with VK(2), there was an increase in gap junctional intercellular communication activity, accompanied by up-regulation of connexin 32 (Cx32), dominantly expressed in normal hepatocyte.
ELISA has confirmed dose dependent increases in connexin 26 in DU-145; connexin 26, 40, and 45 in A549; connexin 32, 40, 43, and 45 in HS-578T; and connexin 45 in IMR-90.