conjugative plasmid


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Related to conjugative plasmid: conjugation, R plasmid

plasmid

 [plaz´mid]
an extrachromosomal self-replicating structure found in bacterial cells that carries genes for a variety of functions not essential for cell growth. Plasmids consist of cyclic double-stranded DNA molecules, replicating independently of the chromosomes and transmitting through successive cell divisions genes specifying such functions as antibiotic resistance (R plasmid); conjugation (F plasmid); the production of enzymes, toxins and antigens; and the metabolism of sugars and other organic compounds. Plasmids can be transferred from one cell to another by conjugation and by transduction. Some plasmids may also become integrated into the bacterial chromosome; these are known as episomes.
conjugative plasmid a plasmid that is transferred from one bacterial cell to another during conjugation.
F plasmid a conjugative plasmid found in F+ (male) bacterial cells that leads with high frequency to its transfer and much less often to transfer of the bacterial chromosome. A cell possessing the F plasmid (F+, male) can form a conjugation bridge (F pilus) to a cell lacking the F plasmid (F, female), through which genetic material may pass from one cell to another.
F′ plasmid a hybrid F plasmid that contains also a segment of the host chromosome.
R plasmid a conjugative factor in bacterial cells that promotes resistance to agents such as antibiotics, metal ions, ultraviolet radiation, and bacteriophage.

con·ju·ga·tive plas·mid

a plasmid that can effect its own intercellular transfer by means of conjugation; this transfer is accomplished by a bacterium's being rendered a donor, usually with specialized pili.

con·ju·ga·tive plas·mid

(kon'jŭ-gā-tiv plaz'mid)
A plasmid that can effect its own intercellular transfer by means of conjugation; this transfer is accomplished by a bacterium being rendered a donor, usually with specialized pili.

conjugative plasmid

a self-transmissible PLASMID that carries genes promoting its own transfer by CONJUGATION. In GRAM-NEGATIVE BACTERIA conjugative plasmids contain a set of transfer (tra) genes, encoding the conjugation apparatus including the SEX PILUS and the gene products for processing and transfer of genetic material. Many conjugative plasmids can mediate the transfer of chromosomal genes between bacteria, which may involve a covalent association between the plasmid and chromosome as in Hfr STRAINS or PRIME PLASMIDS. Conjugative plasmids can also effect the transfer of certain NON-CONJUGATIVE PLASMIDS that are resident in the same cell. Compare NON-CONJUGATIVE PLASMID.
References in periodicals archive ?
The second feature of interest is that in large stably maintained conjugative plasmids, such as R64, functional large addiction operons such as ParA/B or kor/mck usually are present; however, these are lacking in pCT.
Class I borne, multiple-antibiotic resistance encoded by a 150-kilobase conjugative plasmid in epidemic Vibrio cholerae O1 strains isolated in Guinea-Bissau.
It also can share antimicrobial resistance genes through integrons and conjugative plasmids that enable easy transfer of antimicrobial drug resistance genes and thus contribute to spread of antimicrobial resistance (1).
This finding contrasts with some qualities of the other methyltransferases, such as armA and rmtB, which are mostly located on conjugative plasmids (8,13).
Although the remnant transfer region places pO157 in the F-family of conjugative plasmids, the functional transfer region of pO113 places it within the IncI group of self-transmissible plasmids, which includes R64 and ColIb-P9.
Two conjugative plasmids (pCO-1, 160 kb; pCO-2, 150 kb) were extracted from those transconjugants by the Kieser technique (5).