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congenital toxoplasmosis |
Also found in: Encyclopedia, Wikipedia, Hutchinson | 0.02 sec. |
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congenital toxoplasmosis A transplacental infection with the protozoan Toxoplasma gondii affecting ±1⁄3 of fetuses of ♀ with acute acquired toxoplasmosis, most severe if the infection occurs in
1st trimester; children are often normal at birth, followed by blindness, mental retardation; it may affect the brain, lung, heart, eyes, liver Clinical Hydrocephalus, microcephaly, cerebral calcifications, atrophy, chorioretinitis,
uveitis, vitritis, convulsions, hyperbilirubinemia, hepatomegaly Diagnosis PCR of amniotic fluid to detect 35-fold repeat of the B1 gene of T gondii Sensitivity 97%–vs 90% with conventional parasitology Lab IgM immunoassay
Management Pyrimethamine, sulfadiazine, leukovorin. See TORCH. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The rate of congenital toxoplasmosis in the United States is 1-10 per 10,000 live births (4). 2 Other congenital infections Congenital toxoplasmosis 780 General symptoms 780. And depending on the time of infection, congenital toxoplasmosis can cause death, mental retardation, epilepsy or blindness. |
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