congenital leukemia

congenital leukemia

Pediatric hematology A leukemia that develops in the first month of life, usually acute non-lymphocytic leukemia; CL is often associated with congenital malformations and chromsome defects, especially trisomy 21/Down syndrome, but also trisomy 13, mosaic trisomy 9, monosomy 11, Turner syndrome, etc. See Leukemia.
References in periodicals archive ?
It is most often reported in congenital leukemia and AML.
2) Atypical signs reported in trisomy 9 patients include hemivertebra, (3) holoprosencephaly, (4) sex reversal, (5) an unexpectedly normal psychomotor development, (6) no evident external or internal congenital anomalies and congenital leukemia.
MANAGEMENT: Although the severe lymphocytosis could be related to a neonatal viral infection or early pertussis, you suspect that this 2-month-old infant may have congenital leukemia, but the incidence of this cancer is only 1 per 500,000 children.

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