Gilbert syndrome(redirected from congenital familial cholaemia)
fa·mil·i·al non·he·mo·lyt·ic jaun·dice[MIM*143500]
mild jaundice due to increased amounts of unconjugated bilirubin in the plasma without evidence of liver damage, biliary obstruction, or hemolysis; thought to be due to an inborn error of metabolism in which the excretion of bilirubin by the liver is defective, ascribed to decreased conjugation of bilirubin as a glucuronide or impaired uptake of hepatic bilirubin; autosomal dominant inheritance.
Gilbert syndromeA benign hereditary condition (OMIM:143500) in which reduced bilirubin transferase activity results in intermittent hyperbilirubinaemia.
Gilbert syndromeConstitutional liver dysfunction, low-grade chronic hyperbilirubinemia An inherited defect in bilirubin metabolism Clinical Jaundice, weakness, fatigue, nausea, abdominal pain. Cf Criggler-Najjar disease.
Gilbert,Nicholas A., French physician, 1858-1927.
Gilbert disease - Synonym(s): familial nonhemolytic jaundice
Gilbert syndrome - Synonym(s): familial nonhemolytic jaundice