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conformational disease |
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conformational disease, a general term for a number of disorders, such as Alzheimer's disease and Pick's disease, caused by mutations in the structure of specific proteins, leading to the aggregation and deposition of abnormal proteins. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| In recent years our understanding of the nature of spontaneous protein aggregation has increased greatly because of its importance in the pathogenesis of conformational diseases such as amyloidosis, Alzheimer's disease and the spongieform encephalopathies. |
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