acuminatum is a human papillomavirus (HPV)-induced disease.
Lack of efficacy in treating condyloma
acuminata and preventing recurrences with the recombinant quadrivalent human papillomavirus vaccine in a case series of immunocompetent patients.
Anal cancer basics: from condyloma
to invasive cancer (7,8)
are HPV-driven lesions and are known to undergo malignant transformation to squamous cell carcinoma.
Formalin-fixed, paraffin-embedded tissues included 56 anorectal biopsy or surgical resection specimens with the following tissue diagnoses: 29 low-grade squamous intraepithelial lesion (encompasses condyloma
, mild dysplasia, and anal intraepithelial lesion 1), 15 high-grade squamous intraepithelial lesion (encompasses moderate dysplasia, anal intraepithelial lesion 2, severe dysplasia, anal intraepithelial lesion 3, and carcinoma in situ), and 12 invasive squamous cell carcinoma.
HR-HPV types (HPV 16, 18, 31, 35, 39, 45, 51, 52, 56, 59, 66, 68, 69 and 73) are often associated with high grade lesions and invasive cancer, whereas the LR-HPV types (HPV 6, 11, 40, 42, 43, 44, 54, 61, 70, 72, 81, CP6108) are mainly found in low grade lesions, genital or skin warts and condyloma
In the WIHS study published this year, risk factors for condylomas
identified among HIV-positive women were cytologic abnormalities, HPV, smoking, no HAART (highly active antiretroviral therapy), and a low CD4 count, Dr.
The so-called low grade cervical lesions, that is CIN 1 and flat condyloma
(soft, wartlike growths), also carry HPV sequences, however, many of the types identified have been the "low risk" viruses, most commonly 6 and 11 (Kurman, 1994; Lungu et al.
are common in external anogenital areas and less frequent in the cervix and vagina.
Age, y Sex Diagnosis 1 57 M MCC, primary 2 61 F MCC, primary 3 57 F MCC, primary 4 82 F MCC, primary 5 78 M MCC, metastatic 6 80 F MCC, primary 7 65 M MCC, primary 8 81 M MCC, primary 9 60 M MCC, primary 10 61 M Hyperkeratosis 11 49 M Seborrheic keratosis, penis 12 60 M Nonspecific lesion, esophagus 13 40 M Nasal papilloma 14 58 M Anal condylomas
15 44 M Epidermodysplasia verruciformis 16 19 M Cutaneous warts 17 57 F Cutaneous warts 18 64 F Cutaneous nodule 19 6 F Pharyngeal papillomatosis 20 27 M Vocal cord polyp 21 58 M Lichen 22 63 M Skin inflammation 23 72 M Skin inflammation 24 57 M Skin inflammation Patient no.
He advised caution about the diagnosis of VAIN-1, "A lot of us are trying not to make low-grade diagnoses of VIN or VAIN," and instead, "classify the majority of these lesions as flat condylomas
, because the natural history of these low-grade lesions is not really well characterized," Dr.
The new laser procedures include the treatment of bladder tumors, urethral and ureteral strictures, condylomas
, and lesions of the external genitalia, and bladder neck obstructions.