COG7

(redirected from component of oligomeric golgi complex 7)

COG7

A gene on chromosome 16p12.2 that encodes one of the 8 subunits of the conserved oligomeric Golgi (COG) complex, which is required for normal golgi morphology and localisation. COG7 mutations are associated with congenital disorder of glycosylation type IIe.
References in periodicals archive ?
We obtained samples from patients with known glycosylation defects associated with the proteins that are encoded by these genes: mannosyl ([alpha]-1,6-)-glycoprotein [beta]-1,2-N-acetylglucosaminyltransferase (MGAT2); [beta]-1,4-galactosyltransferase 1 (B4GALT1); solute carrier family 35 (CMP-sialic acid transporter), member A1 (SLC35A1; other designation: CMP-sialic acid transporter); solute carrier family 35, member C1 (SLC35C1; other designation: GDP-fucose transporter); component of oligomeric Golgi complex 7 (COG7); and ATPase, H+ transporting, lysosomal V0 subunit a2 (ATP6V0A2).
9] Human genes: MGAT2, mannosyl ([alpha]-1,6-)-glycoprotein [beta]-1,2-N-acetylglucos-aminyltransferase; B4GALT1, [beta]-1,4-galactosyltransferase 1; SLC35A1, solute carrier family 35 (CMP-sialic acid transporter), member A1 (other designation: CMP-sialic acid transporter); SLC35C1, solute carrier family 35, member C1 (other designation: GDP-fucose transporter); COG7, component of oligomeric Golgi complex 7 (other designation: subunit 7 of the conserved oligomeric Golgi complex); ATP6V0A2, ATPase, H+ transporting, lysosomal V0 subunit a2 (other designation: subunit V0 a2 of the lysosomal [H.
Full browser ?