complex disease


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complex disease

Complex trait, polygenetic disease, polygenic disease Genetics A medical condition that arises from a intricate interaction of inherited–'nature' and environmental–'nurture' factors Examples Cancer, CAD, DM, HTN, bipolar disorder, obesity, schizophrenia. Cf Complicated disease, Mendelian genetics.

complex disease

A disease that appears to run in families but whose expression also appears to be influenced by environmental factors.
See also: disease
References in periodicals archive ?
Within one year of launching this product, researchers have conducted genotyping studies that have quickly unveiled key genetic variations for a series of complex diseases.
That situation is complicated further by the possibility that the same complex disease may have multiple genetic and environmental contributors that are neither necessary nor sufficient for a similar phenotype to be expressed (Smith and Lusis 2002).
Using advanced technologies and reagents for DNA methylation research and other genetic analysis applications, researchers have the opportunity to greatly impact the development of new diagnostics and therapeutics for complex diseases, such as cancer.
5, 2015 /PRNewswire/ -- Addressing today's pressing public health challenges, HSRx Group, an Arizona-based biopharmaceutical company, is developing a new generation of combination drugs that dramatically improve treatment and prevention therapies for complex disease conditions.
Genetics will form another area of focus at the future facility, especially because the identification and working of the genetic components of a complex disease can help find cures for them or prevent them from occurring.
Welch Allyn, Skaneateles Falls-based declared about a financing contract reached for Cardiac Insight, a University of Washington spinoff biotech firm, that formulates modernized body worn sensing and computing technologies for applications in cardiology, respiratory and other complex disease states.
A model for forming testable hypotheses in complex disease studies
Multiple Sclerosis is a prototypic debilitating complex disease in which an autoimmune attack is launched against the brain.
This kind of collaboration is a good example of the relationships that must be nurtured if we are to make progress against a complex disease like malaria," said Carter Diggs, MD, PhD, senior advisor of USAID's Malaria Vaccine Development Program.
Freimer actually studies these special abilities in terms of understanding other, more complex disease traits, I thought that was kind of a phenomenal combination of two interests of mine.
Collinge) offer interesting views into complex disease transmission systems.
Even though information gained from genomic studies is providing biological insight on novel targets for the detection and treatment of diseases, often the targets are difficult and their genetic associations only partially explain the incident rate of the complex disease.