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complex disease

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complex disease
Complex trait, polygenetic disease, polygenic disease Genetics A medical condition that arises from a intricate interaction of inherited–'nature' and environmental–'nurture' factors Examples Cancer, CAD, DM, HTN, bipolar disorder, obesity, schizophrenia. Cf Complicated disease, Mendelian genetics.


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However, osteoarthritis is a complex disease that appears to involve a complex series of pathways that include degradation of cartilage, inflammation of the lining of the joint (synovium), and stimulation of pain pathways through different chemical messenger systems.
This is particularly true in the present age, when extreme shortages of pharmacists and other primary health care providers-and competing demands on such personnel-may not allow them to devote sufficient resources to manage complex disease states such as dyslipidemia.
With the goal of stimulating new research and better therapeutics, contributors from epidemiology, physiology, molecular biology, molecular biochemistry and clinical practice offer cross-disciplinary analyses on this complex disease.
 
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