complement-fixation test


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com·ple·ment-·fix·a·tion test

an immunologic test for determining the presence of a particular antigen or antibody when one of the two is known to be present, based on the fact that complement is "fixed" in the presence of antigen and its specific antibody.
See also: Bordet-Gengou phenomenon.

complement-fixation test

any serological test in which complement fixation is detected, indicating the presence of a particular antigen. Specific C-F tests are used to aid in the diagnosis of amebiasis, Rocky Mountain spotted fever, trypanosomiasis, and typhus. They are rarely used in clinical practice today.

com·ple·ment-fix·a·tion test

(kom'plĕ-mĕnt-fik-sā'shŭn test)
An immunologic test for determining the presence of a particular antigen or antibody when one of the two is known to be present, based on the fact that complement is "fixed" in the presence of antigen and its specific antibody.