competitive-binding assay

competitive-binding assay

[kompet′itiv]
Etymology: L, competere, to come together
an analytic procedure based on the reversible binding of a ligand to a binding protein. In proportion to its concentration, the ligand competes with a labeled derivative for binding to the limited number of available binding sites.
References in periodicals archive ?
We investigated the binding ability of CNP and CNP-amino to hAR and hER[alpha] using a receptor competitive-binding assay.
A competitive-binding assay that utilized a novel polyclonal drug antibody was used to quantify LSD in urine.
However, styrene oligomers were reported to have no endocrine disruptive effect both in a MCF-7 cell proliferation assay (10) and in a radioisotope (RI) receptor competitive-binding assay using rat estrogen receptor (10,11).
In conclusion, we have demonstrated an optical tweezers-based immunosensor capable of detecting femtomolar concentrations of antigen in a competitive-binding assay.

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