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competitive inhibitor

   Also found in: Encyclopedia, Wikipedia 0.02 sec.
competitive inhibitor,
an inhibitor of an enzyme reaction that competes with the substrate by binding at the active site.


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It is thought that because of its similarity in ionic size to iodide, the perchlorate ion is a competitive inhibitor of iodide at the sodium iodide symporter (NIS), the plasma membrane protein that catalyzes the accumulation of iodide into thyroid cells (Wolff 1998).
It's a very straightforward competitive inhibitor of the enzyme,' Goldman says.
Abstract 4852: Targeted inhibition of gatekeeper variant "T315I" of Bcr-Abl by a purine-based ATP competitive inhibitor
 
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