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competitive binding assay

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com·pet·i·tive binding assay (km-pt-tv)
n.
An assay in which a biologically specific binding agent competes for radioactively labeled or unlabeled compounds, used especially to measure the concentration of hormone receptors in a sample by introducing a radioactively labeled hormone.


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Competitive binding assays indicated that 17[beta]-estradiol, bisphenol A, and diethylstilbestrol shared a common membrane-binding site.
Pancreatic effects of EDCs: low doses can impair glucagon secretion by Barrett, Julia R. / Environmental Health Perspectives
Macromolecules that bind to functionally relevant sites on a target are used to validate the target for drug discovery and serve as tools for high throughput competitive binding assays to identify quality, small molecule leads for medicinal chemistry programs.
Cetek Corporation and Cubist Pharmaceuticals Expand Collaboration by Business Wire
2000) and on binding ability of 188 chemicals to rat ER using a competitive binding assay (Blair et al.
Screening for estrogen and androgen receptor activities in 200 ... by Kobayashi, Kunihiko / Environmental Health Perspectives
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