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comparative genomic hybridization

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comparative genomic hybridization,
a cytogenetic technique in which reference DNA and the DNA to be studied, as from a tumor or an embryo, are labeled with green- and red-fluorescing fluorochromes, respectively. Genetic abnormalities are detected by changes in the green-to-red ratio.


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We are delighted to announce the world's first pregnancy using real time polar body array Comparative Genomic Hybridization (CGH) and the baby is due later in the spring," the Telegraph quoted Dr Simon Fishel, from the Care Fertility Group in Nottingham, as saying.
Dr Fishel, a former pupil of King David School, Childwall, said: "We are delighted to announce the world's first pregnancy using real-time polar body array Comparative Genomic Hybridization (CGH) and the baby is due later in the spring.
Previous chromosomal comparative genomic hybridization (CGH) studies of papillary thyroid carcinoma (PTC) have demonstrated a low prevalence of aberrations, with the majority of tumors showing no evidence of chromosomal instability.
 
 
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