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community-acquired pneumonia |
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community-acquired pneumonia Pneumonia caused by an infection currently present in the community; CAP is the most common cause of infectious death–US, and number 6 killer overall; of the 57% of CAPs in which a pathogen is identified,
S pneumoniae causes 60%, H influenzae 15%, Legionella pneumophila 10-15%, Staphylococcus aureus 2-10% Clinical Atypical pneumonia with delayed recognition; early SX are distinctly nonpulmonary–eg, dry cough,
myalgia, arthralgia Diagnosis Pathogens in pleural fluid or blood cultures, Pneumocystis carinii in sputum or BAL, a 4-fold ↑ in Mycoplasma pneumoniae antibody titers, isolation of L pneumophila, or a 4-fold ↑ in L
pneumophila antibody titers, or positive direct fluorescent antibody test for legionella, S pneumoniae antigen in serum, urine Risk factors Alcoholism, seizure disorders, smoking, immunosuppression How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The drug is currently also being studied in a second complicated skin infection trial (STRAUSS II) targeting both Gram-positive and Gram-negative bacterial infections, including patients with diabetic foot infections; and in phase III clinical trials in nosocomial pneumonia (CHOPIN studies) and in patients hospitalized with community-acquired pneumonia. During the 2003-04 influenza season, 17 cases of Staphylococcus aureus community-acquired pneumonia (CAP) were reported from 9 states; 15 (88%) were associated with methicillin-resistant S. To investigate reports of severe community-acquired pneumonia, researchers at the Centers for Disease Control and Prevention (CDC) in Atlanta and other institutions studied records of people who last winter developed influenza and then were hospitalized with S. |
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