activity of salicylic acid and the p.
They are also comedolytic
and have intrinsic anti-inflammatory effects, thus targeting two pathogenic factors in acne.
It has keratolytic, fungicidal and bactericidal and comedolytic
The key classes of mechanism of action include antimicrobials, combination therapies, antibacterial and anti-inflammatory, enzyme inhibitors, androgen antagonists, oxidizing agents and comedolytic
The combination drug has a triple-action effect combining the anti-inflammatory and antimicrobial effects of clindamycin with the beneficial comedolytic
effects of tretinoin in normalizing the plugging of pores, which leads to acne lesions.
Finacea(TM) 15% Gel contains 15 % azelaic acid, a naturally occurring substance with anti-inflammatory and comedolytic
activity and very low toxicity.
Differin(TM) Gel is a new synthetic retinoid analogue with advanced receptor selective activity and potent anti-inflammatory and comedolytic
Azelex(R) azelaic acid, a topical anti-acne compound exhibiting anti-inflammatory, antibacterial, and comedolytic
(anti-blackhead) activity, was filed for regulatory approval in Canada in March 1992 and in the U.