combination therapy


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combination therapy

Pharmacology Cocktail therapy The use of multiple agents to treat a clinical condition–eg, cancer, AIDS Reproductive medicine The use of estrogen and progestin as an OC. Cf Chemotherapy, Combined modality therapy, Polypharmacy.

combination therapy

Treatment, especially for cancer, in which various different modalities, such as surgery, radiotherapy or chemotherapy, are used together or sequentially.
References in periodicals archive ?
Tokyo, Japan, Sept 14, 2005 - (JCNN) - Chugai Pharmaceutical announced on September 13 that the Ministry of Health, Labor and Welfare (MHLW) has granted the company with a priority review status for a combination therapy of PEGASYS (pegylated interferon alpha-2a) and rivabirin (planned trade name COPEGUS), two agents manufactured by Chugai.
More patients on combination therapy than monotherapy experienced weight gain (48% vs.
5%) women who received combination therapy transmitted HIV to their infants, compared with 20 of 477(4.
The combination therapy, including drugs meant to block the virus from making copies of itself, had raised great hopes because in many patients it reduced the human immunodeficiency virus in the bloodstream to levels that could not be detected by standard tests.
June 28 /PRNewswire/ -- Preliminary results of a pre-specified subgroup study analysis of patients with diabetes and hypertension demonstrated that the investigational triple combination therapy of olmesartan medoxomil / amlodipine / hydrochlorothiazide (40/10/25 mg) resulted in a statistically significant greater Least Squares (LS) mean reduction in blood pressure from baseline at week 12 (37.
Gabapentin represented 13% of monotherapy prescriptions and, with an atypical antipsychotic, 9% of prescriptions for combination therapy.
While the amount of HIV in the bloodstream can drop to undetectable levels with combination therapy, the effect on the quantity of virus in semen and vaginal secretions has remained unknown.
He then told of another doctor who after a year took his patient off combination therapy that did not include a protease inhibitor.
The Company's scientists demonstrated that mice previously treated with the IgNP/MCT-465 combination therapy which demonstrated tumor remission, remained immune to the development of new cancers even when challenged with a new tumorigenic dose of homologous tumor cells.
The study, presented at the American Society of Hypertension (ASH) annual meeting in New York, also found that at week 12, a significantly greater percentage of patients treated with the investigational triple combination therapy (OM/AML/HCTZ 40/10/25 mg) reached blood pressure goal (<140/90 mm Hg or <130/80 mm Hg for patients with diabetes, chronic renal disease, or chronic cardiovascular disease), as compared to corresponding dual components (64.
Neutel acknowledged that the results from many prior studies had already proved the added efficacy and safety of combination therapy, but he stressed the importance of adding to this evidence base.