colposcopy referral

colposcopy referral

A generic term for the referral of a woman for colposcopy in response to an abnormal pap smear.
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In our initial clinical evaluations of a colposcopy referral population we observed that, compared to conventional NAAT approaches, Xpert HPV delivered better than expected specificity with equivalent sensitivity - meaning equivalent numbers of true positives and significantly fewer false positives in women with negative biopsies," said Dr.
4) However, referrals of low-grade dysplasia to GSH probably represent a small fraction of the true number of women requiring colposcopy, given the low Pap smear rates reported at PHC sites, and the requirement of two low-grade Pap smear abnormalities for colposcopy referral.
Those patients with less than HSIL, however, should undergo a repeat Pap in another 12 months, at which point, evidence of ASC-US or greater warrants a colposcopy referral, he said.
The 2001 guidelines recommended a course of intravaginal estrogen followed by repeat cervical cytology for postmenopausal women, and colposcopy referral for all immunosuppressed women.
Colposcopy results were not collected at the time of the study, as its initial focus was to investigate the most recent incidence of colposcopy referrals (which would indicate a high risk of invasive lesions).
Additionally, in women over age 35 years, HPV testing combined with Pap cytology triage was more specific than cytology alone, and decreased colposcopy referrals and follow-up tests, making this screening option cost effective (J.
11) Although this higher specificity could potentially help reduce colposcopy referrals, widespread adoption of E6E7 mRNA tests will likely be limited by the test's complexity and need for expensive laboratory instruments.
The authors noted that the large number of false-positive HPV results--and the associated colposcopy referrals, risks of overtreatment and costs--were a major limitation of the study.
Martens reported on a secondary end point built into the PATRICIA trial to assess vaccine efficacy in preventing abnormal Pap smear results and subsequent reduction in colposcopy referrals and cervical excision procedures.
Until now it has been impossible to identify which of those women with atypical specimens are at high risk, a situation that results in an unacceptably high proportion of colposcopy referrals.
Cervarix also had a significant impact on colposcopy referrals, with reductions of 26% in the naive group and 10% in the total vaccinated cohort.
The study was conducted to test the hypothesis that colposcopy referrals could be reduced with the use of NMP179 immunoassay.