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colony-stimulating factors (CSF),
a group of glycoprotein growth factors regulating differentiation of myeloid cells. These substances act in either paracrine or autocrine fashion on marrow cells; appear to act synergistically in complex and poorly understood ways; each seems to have the ability to exert action on several lines of progenitor cells, and to influence end cell function.
col·o·ny-stim·u·lat·ing fac·tors(CSF) (kol'ŏ-nē-stim'yū-lāt-ing fak'tŏrz)
A group of glycoprotein growth factors regulating differentiation in myeloid cell lines.
a discrete group of organisms, as a single cluster of bacteria in a culture that was produced from a single starting bacterium.
colonies of pluripotent stem cells located and quantified in the spleen. Colonies grown in vitro interact with erythropoietin to give rise to morphologically identifiable erythroid cells.
cytokines produced by lymphocytes and mononuclear phagocytes which stimulate the growth and differentiation of hematopoietic cells. Includes granulocyte-macrophage colony-stimulating factor, monocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor.