aganglionosis

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Related to colonic aganglionosis: congenital aganglionic megacolon

aganglionosis

 [ah-gang″gle-on-o´sis]
congenital absence of parasympathetic ganglion cells, such as in congenital megacolon.

a·gan·gli·o·no·sis

(ā-gang'glē-ō-nō'sis),
The state of being without ganglia; for example, absence of ganglion cells from the myenteric plexus as a characteristic of congenital megacolon.
[G. ā- priv. + ganglion + -osis, condition]

aganglionosis

/agan·gli·on·o·sis/ (a-gang″gle-on-o´sis) congenital absence of parasympathetic ganglion cells.

aganglionosis

[əgang′lē·ənō′sis]
Etymology: Gk, a, not, gagglion, knot, osis, condition
an absence of parasympathetic ganglion cells in the myenteric plexus, a diagnostic sign of congenital megacolon.

a·gan·gli·o·no·sis

(ā-gang'glē-ŏ-nō'sis)
The state of being without ganglia; e.g., absence of ganglion cells from the myenteric plexus as a characteristic of congenital megacolon.
[G. ā- priv. + ganglion + -osis, condition]

aganglionosis, agangliosis

congenital absence of parasympathetic ganglion cells.

colonic aganglionosis
congenital defect manifested by stenosis, but patency, of the colon, an absence of ganglia of the myenteric plexus and an almost complete absence of skin pigment in white foals resulting from matings between overo horses. The foal develops colic at birth and dies after about 48 hours. See also atresia. Occurs also in some spotted mutant strains of mice. Called also congenital megacolon, aganglionic megacolon.
References in periodicals archive ?
Total colonic aganglionosis and Hirshsprung's disease: shades of the same or different?
Clinical and genetic differences in total colonic aganglionosis in Hirschsprung's disease.
Total colonic aganglionosis, which represents 2% to 5% of all HD cases, is distinct from other forms of HD; it usually has a normal acetylcholinesterase pattern and lacks hypertrophic nerves.