colon polyp


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colon polyp

Gastroenterology A hereditary or acquired pedunculated neoplasm arising from the colonic mucosa; small CPs are usually benign, but may become malignant; like colorectal CA, CPs may present with occult bleeding. See Polyp, Colorectal cancer.
Colon polyp
Acquired polyps Adenomatous or tubular–villous in morphology, ↑ frequency with age; although often asymptomatic, larger polyps are often announced by bleeding or changed bowel habits; if very large, APs may form a leading 'front' of an intussusception; distinction between adenomatous polyps–'tight' round glands and villous adenomas–finger-like fronds of elongated glands has little practical importance–both have malignant potential; periodic colonoscopy and polypectomy yields a 3-fold ↑ in subsequent cancer; hyperplastic polyps are also acquired but are non-neoplastic
Hereditary polyps
• Familial adenomatous polyposis A premalignant, AD condition presenting in early adulthood with 100s to 1000s of colonic polyps, related to a loss of the normal repression of DNA synthesis in the entire colonic epithelium; adenocarcinoma occurs in 70–100% of Pts, prevented by prophylactic colectomy
• Gardner syndrome A rare AD condition with premalignant polyps of the entire GI tract, which is identical to FAP, but has, in addition, extraintestinal tumors; most Pts develop colon carcinoma; other neoplasms in GS Pts include bile duct carcinoma, osteomas of mandible, skull, and long bones, soft tissue tumors–fibromas, lipomas, sebaceous cysts, and rarely, thyroid and adrenal gland cancers
References in periodicals archive ?
iCAD will demonstrate iReveal breast density assessment for 2D and tomosynthesis* mammography, PowerLook Advanced Mammography Platform, and VeraLook colon polyp detection technology
Adenomas are a type of colon polyp that is considered a precursor for invasive colorectal cancer (CRC).
In view of various recommendations on the use of checklists and the recent requirements by ACS CoC of the inclusion of all scientifically validated elements in cancer reports, the purpose of this study was to evaluate the frequency of inclusion of all the scientifically validated elements required by the ACS CoC in surgical pathology cancer reports for colorectal carcinoma, carcinoma in a colon polyp, prostate carcinoma, and breast carcinoma.
While these researchers reported no change in colon polyp recurrence in those who took a standard dose (325 mg), a second study of 517 patients found that this higher dose made polyp recurrence 35% less likely than for patients in a second, placebo group.
Dealers said Wednesday's announcement by the government that Prime Minister Junichiro Koizumi had surgery the same day to remove a colon polyp had only a limited impact on trading as the government said the polyp was benign.
Tests later revealed a colon polyp growth in his large intestine and an infection surrounding his colon.
This large-scale cost-benefit analysis examines how differences in detection rates for adenomas, a type of colon polyp, may affect colorectal cancer outcomes over a lifetime.
As with the precancerous colon polyp, it makes logical sense that if we can eliminate the Barrett's dysplasia completely and safely, we should do so in order to reduce the risk for developing cancer.
Patients with private insurance will no longer be liable for cost sharing when a pre-cancerous colon polyp is removed during screening colonoscopy.
Selenium may reduce the risk of colon cancer, say researchers who re-analyzed three trials on more than 1,700 people who had already had one precancerous colon polyp.
However, the lifetime risk of developing cancer for a patient with Barrett's is similar to the risk of developing colon cancer for a patient with a colon polyp, which is removed immediately upon diagnosis.