collision induced dissociation


Also found in: Acronyms.

collision induced dissociation

A common event in mass spectrometry that follows a collision between an ion and a neutral species, in which part of the ion’s translational energy is converted to internal energy. The internal energy causes dissociation of the ion into smaller ions and may also change its charge.
References in periodicals archive ?
1:45 COLLISION INDUCED DISSOCIATION OF FENBUTATIN OXIDE USING TRIPLE QUADRUPOLE MASS SPECTROMETRY, Montoya LaFrance, * Yassin Jeilani and Victor Ibeanusi, Spelman College, Environmental Science and Studies.
Besides the novel Continuous Accumulation of Selected Ions (CASI[TM]) which allows researchers to enrich selectively the signal from a selected protein or one of its large multiply charged fragments, the Bruker FTMS already includes external collision-cell or internal ICR cell Collision Induced Dissociation (CID), as well as Electron Capture Dissociation (ECD) in the ICR cell.
Other features that make the 6340 an ideal tool for the study of post-translational modifications include the ability to alternate between ETD and collision induced dissociation (CID) modes of fragmentation from scan to scan, which helps to pinpoint the precise identity and location of a chemical modification.
This novel combination further increases the superb resolution and mass accuracy of FTMS by using the latest proprietary high-field magnet technology, while adding facile and efficient precursor mass selection and collision induced dissociation in a conventional Q-q "front end" for on-the-fly data-dependent MS/FTMS fragmentation, or selected accumulation of LC-separated protein digests.

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